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It has been suggested that indole ring of melatonin undergoes the addition of free radical or donation of electron to neutralize the free radicals.44,45 Melatonin has been found to directly scavenge variety of free radicals such as O, OH, ONOO and H2O2.46 Overall oxidative stress, in aerobes, is initiated with the reduction of molecular or ground state oxygen into superoxide anion (O2) free radical which further interact and transform into more toxic free radicals such as OH, ONOO and H2O2

As they entered their second decade, the group faced the challenge of staying relevant in a rapidly evolving J-pop landscape while dealing with numerous lineup changes

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X., Sharpe, A